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CBG: What is Cannabigerol (CBG)?

Cannabigerol, or CBG is one of more than 120 cannabinoids found in the hemp (cannabis) plant. It is showing great promise for treating a variety of ailments.


We’re going to be looking at the newest cannabinoid to rock the health and wellness industry since CBD made its splash a few years back.


What’s interesting about CBG is that it’s sort of an puzzling cannabinoid. Cannabis plants contain only trace amounts, yet it’s considered the “mother of all cannabinoids.” And, because it’s found in such small amounts, it makes it tough to study and research.

“We don’t know much about CBG, it’s not a common cannabinoid” said Perry Solomon, M.D., in an article published on Shape.com. Solomon is a board-certified anesthesiologist and medical cannabis expert.


“You have to be able to get enough to be able to test it and study it.”

With that said, we’re going to share what we do know about this amazing cannabinoid, so you can determine if it’s right for you.


The ‘mother of all cannabinoids’

Before we jump into what all the fuss is about, it’s important to first give an overview of the science behind this cannabinoid, and why it’s considered the “mother” of all other cannabinoids.

You see, cannabinoids start out in an acidic form. Before CBD becomes CBD, it starts out as Cannabidiolic acid (CBDA) and through heat or sunlight the acid burns off and you’re left with CBD. The same is true for THC and other cannabinoids; CBG is the precursor for this.

Cannabigerol (CBG) starts out as Cannabigerolic acid and morphs into other acid based cannabinoids, which in turn through heat and sunlight form into their various non-acid cannabinoids, such as CBD, THC, etc.


What is CBG oil?

So what exactly is CBG? Like CBD, CBG is a non-psychoactive cannabinoid — it won’t make you “feel high.” It’s most abundant in high-CBD hemp plants. High CBG strains also typically contain low levels of THC — the most common cannabinoid that is psychoactive.

CBG works directly on receptors in our brain and nervous system, including CB1 and CB2 receptors, 5-HT1A and alpha-2 receptors, along with the TRPV1 and 2 receptors, and some other cannabinoid receptors. That sounds complex, so just know that brain receptors affect our senses, thoughts, mood, and even our central nervous system.

CBG may even lessen the effects of paranoia sometimes caused by THC.


Possible benefits of CBG

Although medical studies are just getting underway, this compound shows great promise in aiding or treating a number of ailments. We examined a number of published articles and research studies. We found healthline.com had the most thorough list of the medicinal benefits of CBG. Below is a summary of our research:

  • Inflammatory bowel disease. According to a 2013 study conducted on mice, CBG reduced the inflammation that is common with inflammatory bowel disease.

  • Glaucoma. According to a 2008 study, CBG showed promise in treating glaucoma because it reduces intraocular pressure.

  • Bladder dysfunctions. A 2015 study examined the effects of five different cannabinoids on the bladder, and concluded that cannabigerol showed the most promise in treating bladder dysfunctions.

  • Huntington’s disease. According to a 2015 study on mice, this cannabinoid might hold the key in treating neurodegenerative conditions such as Huntington’s disease.

  • Bacterial infections. According to a 2008 study, CBG can kill bacteria, particularly methicillin-resistant Staphylococcus aureus (MRSA). MRSA is a bacterial infection that is hard to treat and dangerous to those with the infection.

  • Colon cancer. According to a 2008 study that looked at colon cancer in rats concluded that CBG might reduce the growth of colon cancer cells and other tumors.

  • Appetite loss. Another study on rats in 2016 showed that CBG might stimulate the appetite. This could prove valuable to those with HIV or cancer.

  • Regulates Mood. Cannabigerol is believed to regulate mood by boosting anandamide, the body’s native cannabinoid ‘bliss’ molecule.

Of course, initial research is just that: an indication that this substance requires closer study. Just because something shows promise in the lab, or on rats, does not mean it will always help people in the real world.


Presently, there are no known interactions when combining CBG with medications. That could change as CBG sees more research and widespread usage. As always, it’s best to check with your doctor before taking CBG or any other cannabinoid.

Users do need to need to be aware when taking medications that come with a grapefruit warning. We know that CBD can bind to the same enzymes that grapefruit does, specifically CYP450 enzymes. That could theoretically cause the body to take longer to process the drug, increasing levels in the bloodstream. Right now, we’re still learning how this works with CBD, so we know even less about CBG.


The most common medication types with grapefruit warnings are:

  • Cholesterol medications

  • Blood pressure medications

  • Heart rhythm medications

  • Anti-infection medications

  • Mood medications

  • Blood thinners

  • Pain medications

  • Erectile dysfunction and prostate medications

Be sure to check with your doctor before combining any of these drugs with CBG or CBD.


To try our CBG concentrate and see if it fits your self-care regimen.




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